Our new Obvious+ tissue clearing approach is the only real technique that delipidates samples without improve in morphology and with small influence on structural integrity.

Megatome can be a vibrating microtome designed to part a broad array of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome allows substantial-throughput tissue sectioning with uniform area profile, as well as minimum tissue damage and knowledge decline.

Antibodies may well choose months to diffuse as a result of just a few millimeters of tissue, which has a steep labeling gradient from area to Main.

Megatome is suitable for precision: the blade vibrates at a better frequency and larger amplitude assortment than other microtomes, and contains a distinctive deflection Handle mechanism.

SE employs a rotational electrical field to disperse extremely electromobile molecules (such as antibodies or surfactant micelles) all over a porous sample with no damaging electrically billed structures within the tissue. This enables two-four day clearing of intact organs,

Our preformulated EasyIndex Option raises and megatomi.com homogenize the refractive index of delipidated tissue samples, rendering them completely clear. This enables gentle penetration into your sample and assures the acquisition of superior-resolution, in-concentrate picture data.

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eFLASH is a quick tissue labeling strategy that enables for uniform complete-organ staining in 20 rounds of labeling.

The SmartSPIM mild sheet microscope offers unparalleled resolution and acquisition speed all over intact tissue volumes, when its modular layout lets you improve and customise particular person elements.

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SHIELD avoids the variability of hydrogel embedding and the information reduction from PFA preservation, guarding specimens for numerous rounds of processing.

Leverage the Obvious+ tissue clearing strategy, in conjunction with eFLASH and patented stochastic electrotransport systems, to promptly very clear and label complete organs. Essential highlights and capabilities include things like:

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